Structural Biology

• Identification of binding partner of orphan immune receptor/ligand
• Structrure-function relationship of cell adhesion molecules (cadherin, nectin etc)
• Structural studies of transcription factor regulation
• Design of split inteins with minimal cross reactivity with other split inteins
• Design of highly specific proteases with minimal undesired cleavage at cryptic sites

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Neurobiology

• Role of Ube3a in autism and Angelman syndrome
• Screening pharmacological inducers/activators of Ube3a and HSF-1
• Epigenetic regulation of learning and long-term memory formation
• Moleular basis of memory extinction
• Chromatin based mechanisms involved in Alzheimer's Disease
  
• Trans-generational inheritance of acquired characters
  

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Immunology

• Effect of nutrients on Th cell development
  
• Role of sex steroid hormones in Th cell development
• Build a network of inflammatory diseases whereby IL-9 play key role
  

Virology

• Studying virus replication machinery
• Virus mediated hijacking of host factors
• Regulation of protein function through post-translational modification

Disease Biology

Allergy
Alzheimer's Disease
Angelman Syndrome
Asthma
Autism
Autoimmune disorders

COVID-19
Influenza
Japanese Encephalitis
Tuberculosis
Tumorigenesis

Drugs and therapeutics development

• Screening pharmacological inducers/activators of Ube3a and HSF-1 for therapy of neurodegenerative as well as learning disorders

PHONE

Office: +91-322-284550
Head: +91-322-284574​

ADDRESS

School of Bioscience
1st and 2nd floor, Life Science Building
Diamond Jubilee Complex
Indian Institute of Technology Kharagpur​​
West Bengal, India. PIN: 721302